Lead programme.

One disease, taken to its root. A published disease model, a proprietary approach, and a defined next gate.

Why Crohn's disease

Ileal Crohn's has a concentrated genetic architecture, making a gene-level approach computationally tractable in a way that the full polygenic landscape isn't.

We already have a published disease model, a proprietary intervention strategy, and a computational pipeline built specifically for this disease. This is existing work, not a starting point.

The next gate is a single-cell validation study with prespecified pass/fail criteria. Wet-lab validation is funding-dependent.

Lead Programme

Ileal Crohn's Disease

Targets 5 candidate genes
IP Proprietary
Advisors 4 across key disciplines
Stage
  1. Discovery
  2. Validation
  3. Single Cell
  4. Preclinical
  5. IND

Computational validation complete. Seeking funding to cross the single-cell validation gate.

Code Indication Organ Modality Stage Addressable
VD-101 Ileal Crohn's disease Ileum Gene-level correction Validation ~3.6M
VD-201 Undisclosed monogenic indication Gene-level correction Discovery
VD-301 Undisclosed monogenic indication Gene-level correction Discovery

Programme codes assigned on entry to the scoring pipeline. Disclosure staged as each candidate clears its prespecified gate.

Request Full Programme Details

Detailed programme data is shared under NDA with qualified partners only. The briefing covers:

Target gene rationale and evidence grading
Intervention design and delivery strategy
IP position and competitive landscape
Preclinical roadmap and funding requirements

Available to investors and academic or industry partners under NDA.

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